CLINDAMED 2.5%

CLINDAMED 2.5%

CLINDAMED 2.5%

Oral Solution

Product description

Composition

Each 100 ml contains:
Clindamycin hydrochloride    2.715 gm
Equi. To Clindamycin base       2.500 gm

Properties

  • Clindamycin is mainly a bacteriostatic antibiotic belonging to the group of lincosamides.
  • Clindamycin is a chlorinated analogue of lincomycin. It works by inhibiting bacterial protein synthesis. The reversible coupling to the sub-unit 50-S bacterial ribosome inhibits translation of amino acids linked to the TRNA, thereby preventing elongation of the peptide chain. That is why the mode of action of clindamycin is predominantly bacteriostatic

Indications

  • Cats: For the treatment of infected wounds and superficial pyoderma caused by clindamycin- sensitive species of Staphylococcus spp. and Streptococcus spp.
  • Dogs: For the treatment of infected wounds, superficial pyoderma and oral cavity/dental infections caused by or associated with clindamycin-sensitive species of Staphylococcus spp., Streptococcus spp., Bacteroides spp., Fusobacterium necrophorum, and Clostridium perfringens.
  • Adjunctive treatment of mechanical or surgical periodontal therapy in the treatment of infections of the gingival and periodontal tissues.
  • For the treatment of osteomyelitis caused by Staphylococcus aureus.

Target species

Cats and dogs

Dosage and Administration

Cats:

  • Infected wounds, superficial pyoderma: approximately 0.5 ml Clindamed 2.5 % oral solution / kg of body weight / 24h or 0.25 ml Clindamed 2.5 % oral solution /kg / 12h for 7 to 10 days

Dogs:

  • Infected wounds, superficial pyoderma and oral cavity/dental infections: approximately
    0.5 ml Clindamed 2.5 % oral solution / kg of body weight / 24h or 0.25 ml Clindamed 2.5 % oral solution /kg / 12h for 7 to 10 days.

Treatment of bone infections (osteomyelitis):

  • approximately 0.5 ml Clindamed 2.5 % oral solution / kg of body weight every 12 hours during a period of 28 days minimum

Warnings & Precautions

  • The treatment should be stopped if no therapeutic effect is observed after 4 days
  • Inappropriate use of the product may increase the prevalence of bacteria resistant to clindamycin. Whenever possible, clindamycin should only be used based on susceptibility testing.
  • In case of administration of high doses of clindamycin or during prolonged therapy of one month or greater, tests for liver and renal functions and blood counts should be performed periodically.

Contra Indications

  • Do not use in rabbits, hamsters, guinea pigs, chinchillas, horses or ruminants because ingestion of clindamycin by these species may cause severe gastrointestinal disorders.
  • Do not use in cases of hypersensitivity to either clindamycin or lincomycin, or to any of the excipients

Side Effects

  • Vomiting and diarrhoea are occasionally observed.
  • Clindamycin sometimes causes the overgrowth of non-sensitive organisms such as resistant clostridia and yeasts.

If super infection occurs, the treatment should be stopped and appropriate measures should be taken based on the clinical situation

Withdrawal time

Not applicable

Storage condition

Store at temperature not exceeding 30ºC and used after opening for 40 days at temperature not exceeding 30ºC

Packaging

10, 15 & 20 ml

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