TYLORESP 20%

TYLORESP 20%

TYLORESP 20%

Injectable Solution

Product description

Composition

Each 100 ml contains
Tylosin tartrate                             21.6 gm
Equivalent to Tylosin base     20.0 gm

Properties

  • Tylosin is a macrolide antibiotic produced by a strain of Streptomyces fradiae.
  • It exerts its antimicrobial effect by inhibiting protein synthesis by binds to 50 S ribosome of susceptible micro-organisms.
  • The Tylosin spectrum of activity includes
    • Gram-positive bacteria.
    • Some Gram-negative strains such as Pasteurella. Mycoplasma spps at concentrations of 16µg/ml or less.
    • It is not generally active against anaerobes.

Indications

  • Tyloresp 20% is indicated in all conditions associated with bacteria sensitive to Tylosin which includes organisms in the following genera: Streptococcus,Bacillus,Staphylococcus,Corynebacterium, Clostridium, Erysipelothrix, Campylobacter, Spirochaetes, Mycoplasma, Fusiformis, Pasteurella and Chlamydia
  • Tyloresp 20% is indicated for use in the treatment of:
    • Cattle:
      • Bovine respiratory complex (shipping fever, pneumonia) caused by Pasteurella multocida and Actinomyces pyogenes
      • Foot-rot (necrotic pododermatitis) and calf diphtheria caused by Fusobacterium necrophorum
      • Metritis caused by Actinomyces pyogenes.
    • Swine:
      • Swine arthritis caused by Mycoplasma hyosynoviae.
      • Swine pneumonia caused by Pasteurella spp.
      • Swine erysipelas caused by Erysipelothrix rhusiopathiae.
      • Acute Swine dysentery associated with Treponema hyodysenteriae.

Target species

Cattle and pigs

Dosage instructions

For Whole Product

Tyloresp 20% should be given by intramuscular injection at the following dose rates:

Cattle and calves:

2 to 5 ml Tyloresp 20% / 100 kg bodyweight once daily for 3 – 5 days.

Pigs:

1 to 5 ml Tyloresp 20% / 100 kg bodyweight once daily for 3 – 5 days.

The maximum injection volume for cattle is limited to 10 ml per injection site.

Warnings & Precautions

  • For administration by the intramuscular route only.
  • Use different injection sites for repeat injections.
  • The maximum injection volume for cattle is limited to 10 ml per injection site.

Contra Indications

  • Do not use in cases of known hypersensitivity to the active ingredient.
  • Do not administer to horses or other equines in which injection of tylosin is fatal.

Side Effects

  • Swelling/inflammation at the site of injection.
  • Vulvular swelling in cattle.
  • Oedema of the rectal mucosa, partial anal protrusion (rosebudding), erythema and pruritus in pigs.
  • Anaphylactic shock and death.

Withdrawal time

Pigs:

  • Meat: 9 days.

Cattle:

  • Meat: 28 days.
  • Milk: 108 hours.

Storage condition

Store at temperature not exceeding 30°C and used after opening for 40 days at temperature not exceeding 30°C.

Packaging

Glass vial : 10, 30, 50, 100, 200, 250. & 500 ml .

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