Composition

Each 1 ml contains:
Ivermectin                                  800 μg

Properties

• Ivermectin belongs Pharmacotherapeuticgroup of anthelmintic 3-AV.
• Ivermectin is a 22, 23-dihydro derivative of an avermectin (which is a fermentation product produced by Streptomyces avermitilis) and consists of two homologues: B1a and B1b. it is a highly effective parasiticide with nematocidal, insecticidal and acaracidal activity documented in a wide range of domesticated animals.
• Avermectins interact with glutamate-gated chloride ion channels, to increase membrane permeability to chloride ions, causing irreversible neuromuscular blockade in nematodes, followed by paralysis and death.

Indications

Sheep:

• The treatment and control of gastrointestinal nematodes, lungworms and nasal bots of sheep.
  Sheep: Gastrointestinal worms (adult and immature):
  Haemonchus contortus, Ostertagia circumcincta, Trichostrongylus spp, Cooperia spp, Nematodirus spp including N. battus, Strongyloides papillosus, Oesophagostomum spp, and adult Chabertia ovina
  Inhibited larval stages and benzimidazole resistant strains of H.contortus and Ostertagia circumcincta are also controlled.
  Lungworms (adult and immature): Dictyocaulus filaria
  Nasal bot (all larval stages): Oestrus ovis

Horses:

• For treatment and control of
  Large Strongyles (adults): Strongylus vulgaris (also early forms in blood vessels), S. edentates (also tissue stages), S. equinus, Triodontophorus spp. including T. brevicauda and T. serratus, and Craterostomum acuticaudatum;
  Small Strongyles (adults, including those resistant to some benzimidazole class compounds): Coronocyclus spp. including C. coronatus, C. labiatus, and C. labratus, Cyathostomum spp. including C. catinatum and C. pateratum, Cylicocyclus spp. including C. insigne, C. leptostomum, C. nassatus, and C. brevicapsulatus, Cylicodontophorus spp., Cylicostephanus spp. including C. calicatus, C. goldi, C. longibursatus, and C. minutus, and Petrovinema poculatum;
  Small Strongyles (fourth-stage larvae);
  Pinworms (adults and fourth stage larvae): Oxyuris equi;
  Ascarids (adults and third- and fourth-stage larvae): Parascaris equorum;
  Hairworms (adults): Trichostrongylus axei;
  Large-mouth Stomach Worms (adults): Habronema muscae;
  Bots (oral and gastric stages): Gasterophilus spp. including G. intestinalis and G. nasalis;
  Lungworms (adults and fourth-stage larvae): Dictyocaulus arnfieldi;
  Intestinal Threadworms (adults), Strongyloides westeri;
  Summer Sores caused by Habronema and Draschia spp. cutaneous third- stage larvae; Dermatitis caused by neck threadworm microfilariae, Onchocerca species

Target species

Sheep & horses.

Dosage instructions

Route of administration: administered orally,
For Whole Product:

Sheep:

• 2.5 ml Osimectin 80 / 10 kg bodyweight as a single dose.

Horses:

• 2.5 ml Osimectin 80 / 10 kg bodyweight as a single dose.

Warnings:

• Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
  • Too frequent and repeated use of anthelmintics from the same class, over an extended period of time
  • Underdosing which may be due to underestimation of body weight, misadministration of the product or lack of calibration of the dosing device (if any).
• Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.

Precautions

Precautions for humans:

• Do not smoke, drink or eat while handling the product.
• Avoid contact with skin and eyes. In case of accidental eye or skin contact, wash the affected area with clean running water immediately. Seek medical attention if irritation persists.
• Wash hands after use.

Precautions for animals:

• None.

Precautions during pregnancy, lactation and laying:

• The product can be administered to ewes at any stage of pregnancy or lactation provided that the milk is not used for human consumption.
• Horses of all ages, including pregnant mares and breeding stallions, have been treated with no adverse effect

Contra Indications

• The product has been formulated specifically for use in sheep. It should not be used in other species, adverse reactions, including fatalities in dogs, may occur.

Drug-drug interaction

None Known

Side Effects

Some animals may cough slightly immediately after treatment. This is a temporary occurrence and is of no clinical consequence.

Poisoning:

No antidote has been identified; however symptomatic treatment may be beneficial.

Withdrawal time

• Sheep may not be slaughtered for human consumption until 14 days after the last treatment.
• Do not use in sheep producing milk for human consumption.

Storage condition

Store at temperature not exceeding 30°C

Packaging

Carton box containing high density polyethylene plastic bottle of 50, 100, 125, 250, 500, 1000, 5000 & 10000 ml with outer label + insert leaflet.