Composition

Each 100 ml contains:
Levamisole Hydrochloride       3.0 gm
Oxyclozanide                                   6.0 gm

Properties

• Levamisole is an imidazothiazole that acts by interfering with parasite nerve transmission causing muscular paralysis. It is effective against adult and immature gastrointestinal roundworm and lungworm infections.
• Oxyclozanide is a salicylanilide, which is mainly active against adult liver flukes. It is distributed to the liver, kidney and intestines and is excreted in the bile.

Indications

• For the treatment of both gastrointestinal and pulmonary nematode infections, and adult liver fluke infections.
• Levamisole is effective against mature and developing immature stages of a wide range of important nematode species and is highly effective against the following:
  • Lungworms: Dictyocaulus spp.
  • Gastrointestinal worms: Trichostrongyles spp., Cooperia spp., Ostertagia spp. (except inhibited Ostertagia larvae), Haemonchus spp., Nematodirus spp., Bunostomum spp.Oesophagostomum spp., Chabertia spp.
• Treatment of chronic fascioliasis caused by the adult stage of Fasciola hepatica, sensitive to oxyclozanide.
• Elimination of gravid tapeworm segments (Moniezia spp).
• The product removes most mature Fasciola spp (flukes) present in the bile ducts of the liver.

Target species

Cattle, Sheep

Dosage instructions

Route of administration: by oral administration.

For Whole Product:

Cattle:

• 2.5 ml per 10 kg bodyweight in a single oral administration.

Sheep:

• 0.5 ml per 2 kg bodyweight in a single oral administration

Warnings & Precautions

• Shake the container well before use
• Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
  • Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
  • Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device (if any).
• Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.

After treatment, animals should be moved to clean pasture in order to prevent re-infection.

Contra – Indications:

• Animals must not be treated within a period of 14 days before or after treatment with organophosphorus compounds.
• This product must not be used in cattle and sheep producing milk for human consumption.

Side Effects

• At normal oxyclozanide dose levels, cattle may show slight softening of the faeces with the occasional animal showing increased frequency of defecation and transient inappetence.
• Rarely, sheep may show an anaphylactic reaction with swelling of the head.

Withdrawal time

• Cattle (meat & offal): 5 days
• Sheep (meat & offal): 5 days

Storage condition

Store at temperature not exceeding 30°C

Packaging

Opaque HDPE plastic bottles containing 10, 30, 50, 100, 125, 200, 250, 300, 500 ml, 1, 2, 5, 10, 20, 25 L oral suspension with HDPE plastic caps, containing (LDPE) plastic linear foam with outer label containing data