ALBENDAZOLE 20%

ALBENDAZOLE 20%

ALBENDAZOLE 20%

Oral Suspension

Product description

Composition

Each 100 ml contains:

Albendazole               20 gm

Properties

A broad spectrum multi-purpose anthelmintic for the mature and developing immature forms of gastrointestinal roundworms, lungworms, tapeworms and adult liver fluke in cattle and sheep.
The product is also ovicidal against fluke and roundworm eggs.
Benzimidazoles bind to nematode tubulin, a protein necessary for the formation and viability of microtubules. This occurs primarily in absorptive intestinal cells resulting in the absence of microtubules in the intestinal cells of the nematode, with the result that these cells cannot absorb nutrients, thus causing a consequent reduction in glycogen and effective starvation of the parasites. Structural differences have been shown to exist between tubulin from mammalian and helminth sources, resulting in the preferential toxicity of albendazole to the helminth and not to the host. Benzimidazoles have also been shown to inhibit the fumarate reductase system of helminths and impair energy production.

Indications

  •  In cattle it is active against the following species:
    • Roundworms: Ostertagia, Haemonchus, Trichostrongylus, Nematodirus, Oesophagostomum, Bunostomum, Cooperia, and Strongyloides spp. It is usually effective against inhibited larvae of Cooperia and Ostertagia,
    • Lungworms: Dictyocaulus viviparus,
    • Tapeworms: Moniezia spp.,
    • Adult liver fluke: Fasciola hepatica.
  • In sheep it is active against benzimidazole- susceptible strains of the following species:
    • Roundworms: Ostertagia, Haemonchus, Trichostrongylus, Nematodirus (including N. Battus), Chabertia and Oesophagostomum. It is usually effective against inhibited larvae of Ostertagia,
    • Lungworms: Dictyocaulus filaria,
    • Tapeworms: Moniezia spp.,
    • Adult liver fluke: Fasciola hepatica.
  • The product is ovicidal and will kill fluke and roundworm eggs, thus reducing pasture contamination.

Target species

Cattle and sheep

Dosage and Administration

Rote of administration: For oral administration.
Dose for whole product:

Cattle:

  • Worm dose: For the control of roundworms, lungworms, tapeworms and fluke and roundworm eggs.
    • Dosage: 3.75 ml of product /100 kg bodyweight. (repeat after 21 days).
  • Fluke and worm dose: For the additional treatment of adult liver fluke (chronic fascioliasis) in cattle:
    • Dosage: 5 ml of product / 100 kg bodyweight. (repeat after 21 days).

Sheep:

  • Worm dose: For the control of roundworms, lungworms, tapeworms, fluke and roundworm eggs.
    • Dosage: 2.5 ml of product / 100 kg bodyweight. (repeat after 21 days).
  • Fluke and worm dose: For the additional treatment of adult liver fluke (chronic fascioliasis) in sheep.
    • Dosage: 3.75 ml of product / 100 kg bodyweight. (repeat after 21 days).

Warnings & Precautions

  • Do not dose ewes at the ‘fluke and worm’ dose rate, (7.5 mg/kg), during tupping or for 1 month after removing the rams.
  • Not for use in sheep producing milk for human consumption.
  • Cattle suffering from severe lung damage due to heavy lungworm infestation may continue to cough for some weeks after infection.
  • Care must be taken not to damage the pharyngeal region during dosing, particularly in sheep.
  • Shake well before use.

Contra Indications

Do not use in cases of known hypersensitivity to the active ingredient

Side Effects

None known

Withdrawal time

Cattle:

  • Meat & Offal: 14 days
  • Milk: 60 hours

Sheep:

Meat & Offal: 5 days

Not to be used in sheep producing milk for human consumption

Storage condition

Store at temperature not exceeding 30°C and used after opening for 40 days at temperature not exceeding 30°C

Packaging

HDPE plastic bottle with HDPE plastic cap, LDPE liner foam filled with 50, 100, 125, 250, 500 ml, 1 Liter, 5 and 10 Liter with outer label containing data.

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