Composition
Each 1 ml contains:
Ketoprofen base 100 mg
Properties
Ketoprofen is a derivative of phenylpropionic acid, and belongs to the non-steroidal anti-inflammatory drugs. Like all such substances, its principal pharmacological actions are anti-inflammatory, analgesic and anti-pyretic. The mechanism of action is related to the ability of ketoprofen to interfere with the synthesis of prostaglandins from precursors such as arachidonic acid.
Indications
For Horse, Cattle, Pig, Dogs & Cats:
Horse:
- The alleviation of inflammation and pain associated with musculoskeletal disorders.
- The alleviation of visceral pain associated with colic.
Cattle:
- The supportive treatment of parturient paresis associated with calving.
- Reducing the pyrexia and distress associated with bacterial respiratory disease when used in conjunction with antimicrobial therapy as appropriate.
- Improving the recovery rate in acute clinical mastitis, including acute endotoxin mastitis, caused by Gramnegative micro-organisms, in conjunction with antimicrobial therapy.
- Reducing oedema of the udder associated with calving.
Pigs:
- Reducing the pyrexia and respiratory rate associated with bacterial or viral respiratory disease when used in conjunction with antimicrobial therapy as appropriate.
- The supportive treatment of Mastitis Metritis Agalactia Syndrome in sows, in conjunction with antimicrobial therapy as appropriate.
Dogs & Cats:
- Inflammation and pain associated with musculoskeletal disorders.
Target species
Horse, Cattle, Pig, Dogs & Cats
Dosage instructions
Horse:
By Intravenous administration.
- For use in musculo-skeletal conditions: 1 ml of KETOMED 10% / 45 kg body weight, once daily for up to 3 to 5 days.
- For use in equine colic: 1 ml of KETOMED 10% / 45 kg body weight given by intravenous injection for immediate effect, a second injection may be given if colic recurs.
Cattle:
By Intravenous or intramuscular administration: 3 ml of KETOMED 10% / 100 kg body weight, once daily for up to 3 days.
Pigs :
By Intramuscular administration: 1 ml of KETOMED 10%/33 kg body weight.
Dogs:
By subcutaneous, intramuscular or intravenous injection: 0.2 ml of product per 10 kg once daily for up to 3 days.
Cats :
By subcutaneous injection: 0.2 ml of product per 10 kg once daily for up to 3 days.
Warnings & Precautions
- The use of ketoprofen is not recommended in foals under the age of 15 days. Use in any animal less than 6 weeks of age or in aged animals may involve additional risk. If such use cannot be avoided animals may require a reduced dosage and careful management.
- Avoid use in any dehydrated, hypovolaemic or hypotensive animals as there is a potential risk of increased renal toxicity.
- Avoid intra-arterial injection.
- Do not exceed the stated dose or duration of treatment.
Contra Indications
- Do not administer with other non-steroidal anti-inflammatory drugs (NSAIDs) concurrently or within 24 hours of each other, corticosteroids, diuretics or anticoagulants.
- Some NSAIDs may be highly bound to plasma proteins and compete with other highly bound drugs which can lead to toxic effects.
- Concurrent administration with nephrotoxic drugs should be avoided.
- Do not use in newborn domestic animals due to presence of benzyl alcohol in product as preservative.
Side Effects
- In very rare cases, due to the action of inhibition of prostaglandin synthesis, there can be the possibility in certain individuals of gastric or renal intolerance.
- In very rare cases allergic reactions may occur.
Withdrawal time
Cattle:
- Meat and offal:
- following intravenous administration: 1 day
- following intramuscular administration: 2 days
- Milk: zero hours
Horses:
- Meat and offal: 1 day
- Milk: Not authorized for use in lactating animals producing milk for human consumption
Pigs:
- Meat and offal: 2 days
Storage condition:
Store at temperature not more than 30◦C and used for 28 days after opening at temperature not more than 30◦C away from sun light.
Packaging
Glass vials :10, 30, 50, 100, 200, 250 &500 ml