KETOMED 10%

Injectable Solution

Product description

Composition

Each 1 ml contains:
Ketoprofen base             100 mg

Properties

Ketoprofen is a derivative of phenylpropionic acid, and belongs to the non-steroidal anti-inflammatory drugs. Like all such substances, its principal pharmacological actions are anti-inflammatory, analgesic and anti-pyretic. The mechanism of action is related to the ability of ketoprofen to interfere with the synthesis of prostaglandins from precursors such as arachidonic acid.

Indications

For Horse, Cattle, Pig, Dogs & Cats:

Horse:

  • The alleviation of inflammation and pain associated with musculoskeletal disorders.
  • The alleviation of visceral pain associated with colic.

Cattle:

  • The supportive treatment of parturient paresis associated with calving.
  • Reducing the pyrexia and distress associated with bacterial respiratory disease when used in conjunction with antimicrobial therapy as appropriate.
  • Improving the recovery rate in acute clinical mastitis, including acute endotoxin mastitis, caused by Gramnegative micro-organisms, in conjunction with antimicrobial therapy.
  • Reducing oedema of the udder associated with calving.

Pigs:

  • Reducing the pyrexia and respiratory rate associated with bacterial or viral respiratory disease when used in conjunction with antimicrobial therapy as appropriate.
  • The supportive treatment of Mastitis Metritis Agalactia Syndrome in sows, in conjunction with antimicrobial therapy as appropriate.

Dogs & Cats:

  • Inflammation and pain associated with musculoskeletal disorders.

Target species

Horse, Cattle, Pig, Dogs & Cats

Dosage instructions

Horse:

By Intravenous administration.

  • For use in musculo-skeletal conditions: 1 ml of KETOMED 10% / 45 kg body weight, once daily for up to 3 to 5 days.
  • For use in equine colic: 1 ml of KETOMED 10% / 45 kg body weight given by intravenous injection for immediate effect, a second injection may be given if colic recurs.

Cattle:

By Intravenous or intramuscular administration: 3 ml of KETOMED 10% / 100 kg body weight, once daily for up to 3 days.

Pigs :

By Intramuscular administration: 1 ml of KETOMED 10%/33 kg body weight.

Dogs:

By subcutaneous, intramuscular or intravenous injection: 0.2 ml of product per 10 kg once daily for up to 3 days.

Cats :

By subcutaneous injection: 0.2 ml of product per 10 kg once daily for up to 3 days.

Warnings & Precautions

  • The use of ketoprofen is not recommended in foals under the age of 15 days. Use in any animal less than 6 weeks of age or in aged animals may involve additional risk. If such use cannot be avoided animals may require a reduced dosage and careful management.
  • Avoid use in any dehydrated, hypovolaemic or hypotensive animals as there is a potential risk of increased renal toxicity.
  • Avoid intra-arterial injection.
  • Do not exceed the stated dose or duration of treatment.

Contra Indications

  • Do not administer with other non-steroidal anti-inflammatory drugs (NSAIDs) concurrently or within 24 hours of each other, corticosteroids, diuretics or anticoagulants.
  • Some NSAIDs may be highly bound to plasma proteins and compete with other highly bound drugs which can lead to toxic effects.
  • Concurrent administration with nephrotoxic drugs should be avoided.
  • Do not use in newborn domestic animals due to presence of benzyl alcohol in product as preservative.

Side Effects

  • In very rare cases, due to the action of inhibition of prostaglandin synthesis, there can be the possibility in certain individuals of gastric or renal intolerance.
  • In very rare cases allergic reactions may occur.

Withdrawal time

Cattle:

  • Meat and offal:
    • following intravenous administration: 1 day
    • following intramuscular administration: 2 days
  • Milk: zero hours

Horses:

  • Meat and offal: 1 day
  • Milk: Not authorized for use in lactating animals producing milk for human consumption

Pigs:

  • Meat and offal: 2 days

Storage condition:

Store at temperature not more than 30◦C and used for 28 days after opening at temperature not more than 30◦C away from sun light.

Packaging

Glass vials :10, 30, 50, 100, 200, 250 &500 ml