Composition
Each 100 ml contains:
Oxytetracycline HCL 21.6 gm
Equivalent to Oxytetracycline base 20.0 gm
Properties
- Oxytetracycline is a bacteriostatic antibiotic that inhibits protein synthesis in susceptible bacteria. Inside the cell it binds irreversibly to receptors on the 30S subunit of the bacterial ribosome where it interferes with the binding of the aminoacyl-transfer RNA to the acceptor site on the messenger RNA ribosome complex. This effectively prevents the addition of amino acids to the elongating peptide chain, inhibiting protein synthesis. The product is specifically formulated to provide a prolonged action resulting in sustained antibacterial activity.
- Oxytetracycline had been shown to be effective in vitro against the following bacterial species: Bordetella bronchiseptica, Corynebacterium pyogenes, Erysipelothrix rhusiopathiae, Escherichia coli, Haemophilus somnus, Pasteurella haemolytica, Pasteurella multocida, Salmonella dublin, Staphylococcus aureus, Streptococcus agalactiae, Streptococcus faecalis, Streptococcus pyogenes and Streptococcus uberis.
Indications
The product is indicated for use in cattle, sheep and pigs in the treatment of:
- Atrophic rhinitis caused by Bordetella bronchiseptica, Mannheimia haemolytica and Pasteurella multocida.
- Navel/jointill caused by Arcanobacterium pyogenes, E. coli or Staphylococcus aureus.
- Mastits caused by Corynebacterium pyogenes, E. coli, Staphylococcus aureus, Streptococcus agalactiae or Streptococcus uberis.
- Metritis caused by E. coli or Streptococcus pyogenes.
- Pasteurellosisand infections of the respiratory tract caused by Mannheimia haemolytica and Pasteurella multocida.
- Septicaemia caused by Salmonella dublin and Streptococcus pyogenes.
- Erysipelas caused by Erysipelothrix rhusiopathiae.
The product can also be used in the control of enzootic abortion in sheep.
Target species
Cattle, sheep and pigs
Dosage & Administration
For whole product:
By deep intramuscular injection to cattle, sheep and pigs.
The recommended dosage rate is 1 ml Oxy 20% L.A / 10 kg bodyweight for a single administration only and repeat after 2-4 days.
Warnings & Precautions
- Maximum recommended dose at any one site: Cattle 20 ml, Pigs 10 ml, Sheep 5 ml
- Piglets: 1 day 0.2 ml, 7 days 0.3 ml, 14 days 0.4 ml, 21 days 0.5 ml and over 21 days 1 ml/ 10 kg
- Do not dilute the product.
- If concurrent treatment is administered, use a separate injection site.
Contra Indications
- Not for use in horses, dogs, cats.
- Not for use in animals suffering from hepatic or renal damage.
- Not for use in animals have hypersensitivity to tetracyclines
- It should not be used in newly born domestic animals
Side Effects
- The use of tetracyclines during the period of tooth and bone development, including late pregnancy, may lead to discolouration.
- Although the product is well tolerated, occasionally a local reaction of a transient nature may be observed
Withdrawal time
Cattle:
- Meat : 31 days
- Milk : 10 days
Sheep:
- Meat : 21 days
- Milk : not used in lactating ewes.
Pigs:
- Meat : 18 days
Storage condition:
Store at temperature not exceeding 30°C and used after opening for 50 days at temperature not exceeding 30°C.
Packaging
Glass vials :10, 30 ,50 ,100, 200, 250 & 500 ml