Composition

Each 100 ml contains:
Rafoxanide                            7.5 gm

Properties

• Rafoxanide acts by uncoupling oxidative phosphorylation of flukes, including reduced ATP levels, decreased glycogen content and accumulation of succinate.
• Rafoxanide also binds strongly to plasma proteins and is inactive until ingested by the parasite and separated from the plasma albumin by digestion. For this reason rafoxanide does not affect the host’s mitochondria in vivo. Only blood-sucking nematodes and flukes residing in the bile, through which salicylanilides are excreted from the host’s body, are susceptible to rafoxanide

Indications

• Rafoxanide is used as fasciolicide in cattle and, sheep active against adult and immature flukes aged 6 to 8 weeks and older.
• Rafoxanide is also active against gastrointestinal nematodes (Haemonchus, Bunostomum, Oesophagostomum, and Gaigeria species) and against the sheep nasal bot fly (Oestrus ovis)..

Target species

Cattle and Sheep & Goats

Dosage instructions

By S/C inj. only

Cattle:

• 1 ml RAFOXANIDE 7.5% / 10 kg bodyweight.

Sheep & Goats:

• 2.5 ml RAFOXANIDE 7.5% / 25 kg bodyweight

Warnings & Precautions

For S/C injection only.

Contra Indications

• Do not administer to animals with known hypersensitivity to the active ingredient.
• It should not be used in newly born domestic animals.

Side Effects

None known

Withdrawal time

Meat – 28 days

Storage condition

Store in temperature not exceeding 30°C. And used after opening for 30 days at temperature not exceeding 30°C.

Packaging

Glass vials : 10, 30, 50, 100 200, 250 & 500 ml.